Lawrence J Appel Selected Research

Nephrosclerosis

1/2013	Mineral metabolites and CKD progression in African Americans.
7/2012	Net endogenous acid production is associated with a faster decline in GFR in African Americans.
3/2009	G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions.
11/2006	Cardiovascular outcomes in the African American Study of Kidney Disease and Hypertension (AASK) Trial.
10/2006	Baseline predictors of renal disease progression in the African American Study of Hypertension and Kidney Disease.

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Lawrence J Appel Research Topics

Disease

83	Hypertension (High Blood Pressure) 01/2022 - 10/2002
49	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 11/2002
35	Chronic Renal Insufficiency 01/2022 - 07/2003
33	Kidney Diseases (Kidney Disease) 01/2022 - 11/2002
25	Weight Loss (Weight Reduction) 03/2022 - 10/2002
18	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 07/2003
16	Overweight 01/2022 - 10/2002
14	Inflammation (Inflammations) 01/2022 - 07/2003
12	Proteinuria 01/2019 - 10/2005
12	Stroke (Strokes) 10/2018 - 06/2006
11	Obesity 03/2022 - 06/2006
10	Insulin Resistance 02/2021 - 01/2005
9	Orthostatic Hypotension (Postural Hypotension) 01/2022 - 01/2017
9	Gout 07/2021 - 06/2005
9	Prehypertension 01/2018 - 09/2007
9	Atherosclerosis 01/2018 - 02/2003
8	Coronary Disease (Coronary Heart Disease) 04/2017 - 10/2003
7	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 06/2006
6	Heart Diseases (Heart Disease) 01/2022 - 11/2006
6	Heart Failure 01/2018 - 09/2013
5	Neoplasms (Cancer) 01/2021 - 10/2003
5	Chronic Disease (Chronic Diseases) 01/2020 - 06/2005
5	Infections 01/2020 - 06/2006
5	Nephrosclerosis 01/2013 - 10/2006
4	Syncope (Fainting) 01/2022 - 01/2017
4	Body Weight (Weight, Body) 12/2021 - 07/2006
4	Hyperkalemia 01/2020 - 09/2009
4	Hypotension (Low Blood Pressure) 01/2020 - 11/2005
4	Atrial Fibrillation 04/2017 - 06/2006
3	Type 2 Diabetes Mellitus (MODY) 03/2022 - 04/2006
3	Breast Neoplasms (Breast Cancer) 01/2022 - 10/2012
3	Dizziness (Lightheadedness) 01/2019 - 01/2017
3	Myocardial Infarction 01/2018 - 01/2009
3	Carotid Stenosis (Carotid Artery Stenosis) 02/2011 - 06/2006
3	Dyslipidemias (Dyslipidemia) 02/2011 - 06/2006
3	Migraine Disorders (Migraine) 02/2011 - 06/2006
3	Thrombophilia 02/2011 - 06/2006
3	Hyperhomocysteinemia 02/2011 - 06/2006
3	Substance-Related Disorders (Drug Abuse) 02/2011 - 06/2006
3	Sickle Cell Anemia (Hemoglobin S Disease) 02/2011 - 06/2006
3	Sleep Apnea Syndromes (Sleep Apnea) 02/2011 - 06/2006
3	Isolated Systolic Hypertension 12/2008 - 02/2006
2	Frailty 10/2022 - 03/2017

Drug/Important Bio-Agent (IBA)

52	SodiumIBA 01/2022 - 10/2002
28	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2003
23	CreatinineIBA 01/2019 - 07/2003
21	Antihypertensive Agents (Antihypertensives)IBA 01/2022 - 11/2002
19	PotassiumIBA 11/2021 - 10/2002
13	hydroxide ionIBA 10/2022 - 09/2009
13	SaltsIBA 12/2021 - 07/2003
13	Uric Acid (Urate)IBA 07/2021 - 06/2005
12	Biomarkers (Surrogate Marker)IBA 03/2022 - 01/2016
12	CarbohydratesIBA 01/2022 - 11/2005
11	CholesterolIBA 01/2017 - 07/2003
8	Vitamin D FDA LinkGeneric 10/2022 - 10/2003
8	Phosphorus (Red Phosphorus)IBA 10/2021 - 10/2006
8	HDL CholesterolIBA 02/2021 - 01/2005
8	Glucose (Dextrose)FDA LinkGeneric 02/2021 - 10/2005
8	LipidsIBA 01/2020 - 07/2003
7	Unsaturated FatsIBA 01/2022 - 11/2005
7	Ramipril (Altace)FDA LinkGeneric 10/2018 - 07/2003
7	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 09/2017 - 07/2003
6	C-Reactive ProteinIBA 10/2021 - 07/2012
6	MineralsIBA 10/2021 - 10/2006
6	AcidsIBA 01/2019 - 07/2011
6	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2018 - 11/2002
6	LDL CholesterolIBA 07/2017 - 11/2005
6	Triglycerides (Triacylglycerol)IBA 12/2014 - 11/2005
6	Hormones (Hormone)IBA 10/2012 - 06/2006
5	Metformin (Glucophage)FDA LinkGeneric 03/2022 - 01/2021
5	Fibroblast Growth Factor-23IBA 10/2021 - 07/2012
5	Insulin (Novolin)FDA Link 02/2021 - 05/2013
5	Lipoproteins (Lipoprotein)IBA 01/2020 - 06/2006
5	Metoprolol (Toprol-XL)FDA LinkGeneric 10/2018 - 04/2006
5	Amlodipine (Norvasc)FDA LinkGeneric 10/2018 - 04/2006
5	Dietary SodiumIBA 12/2017 - 04/2007
5	Lipoprotein(a)IBA 01/2014 - 01/2005
4	25-hydroxyvitamin DIBA 10/2022 - 12/2009
4	Dietary PotassiumIBA 07/2021 - 12/2017
4	AlbuminsIBA 01/2020 - 06/2013
4	CalciumIBA 01/2020 - 10/2003
4	Urea (Carbamide)FDA LinkGeneric 01/2019 - 10/2006
4	NitrogenIBA 01/2019 - 10/2006
4	Fish OilsIBA 01/2018 - 11/2002
4	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 09/2017 - 04/2006
3	FatsIBA 12/2021 - 07/2006
3	SugarsIBA 12/2021 - 07/2006
3	HDL LipoproteinsIBA 02/2021 - 08/2010
3	Parathyroid Hormone (Parathormone)IBA 01/2020 - 12/2009
3	Fibrinogen (Factor I)FDA Link 01/2020 - 07/2012
3	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2018 - 06/2009
3	Cystatin CIBA 01/2017 - 12/2011
3	Phosphates (Orthophosphate)IBA 01/2016 - 07/2012
3	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2016 - 05/2012
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 02/2011 - 06/2006
3	Oral ContraceptivesIBA 02/2011 - 06/2006
3	SmokeIBA 02/2011 - 06/2006

Therapy/Procedure

33	Dietary Approaches To Stop Hypertension 03/2022 - 11/2002
17	Therapeutics 01/2022 - 12/2002
6	Drug Therapy (Chemotherapy) 01/2022 - 02/2006